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Although often presented as a broadly beneficial polyphenol, resveratrol has also been repeatedly flagged as a potentially PAINS-susceptible molecule, owing to its redox activity, metal-chelating properties, and tendency to interfere with multiple assay formats in a non-specific manner as highlighted in the Nature commentary ( Weight of evidence: Overall evidence is Low : an add-on signal on hyperactivity without core-symptom change

Again, more is not betteronce you reach the saturation point, any additional intake will be superfluous

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However, the cause of this decrease is yet to be determined

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16.Bjekic MD, Vlajinac HD, Sipetic SB, Marinkovic JM