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Ferrocenecarboxylic acid was purchased from Abcr

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All experiments were conducted according to the manufacturer's guidelines

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doi: 10.1038/s41564-018-0307-3

Overexpression of Sfrp5 has been shown to increase phosphorylated AMPK (p-AMPKThr172), upregulate MFN1/2, downregulate mitochondrial fission proteins, and enhance mitochondrial biogenesis while reducing oxidative stress 130