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The investigators reported that oral AOD-9604 administration in rodent models produced measurable increases in fat oxidation and reductions in body fat, and that direct application of the compound to ex vivo human adipose tissue produced concentration-dependent increases in lipolysis [2]

The Broad Institute of MIT and Harvard (Cambridge, MA, USA) has created the Connectivity Mapa publicly available library of transcriptional responses to known perturbagens, substances that modulate gene expression [3]

Diazolidinyl Urea slowly breaks down into formaldehyde, an effective microbe killer but also a known allergen/carcinogen

10.1093/hmg/ddr475 Hum

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One randomized trial reported increases in body stores after six months, while other trials have shown mixed results, so the picture is still developing [1][2]