glutathione pathway brain Metabolism and functions of in Frontiers | Glutathione and neurodegenerative

In human neuronal cells and APP SWE /PS1 E9 murine model of AD, infection induces A accumulation, NLRP3 activation, neuroinflammation and cytotoxicity, and chronic infection exacerbates neuropathology and cognitive decline

R-Y W, Qui YH, Yoo SY, McQueen T, Chen Y, Zeng Z, Coombes KR, Schober W, Konopleva M, Kornblau SM, Andreeff M

did note a significant decrease in levels of GSH, GPx activity, and GST-M [22,23]

Chronic alcohol consumption increases the number of recruited macrophages in the liver, promoting the differentiation of Ly6C hi monocytes into pro-inflammatory macrophages that contribute to tissue damage [47]

E.KuehnelM.HaverichA.WelteT.LaengerF.et al (2020)

One of the noninvasive strategies to treat these disorders is to control melanogenesis by inhibiting tyrosinase gene expression