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p = 0.0005), while the MeHg + Aa group (103.4 0.884%) did not express a significant difference in relation to the control (100.2 0.993%

Compared to a natural history cohort comprising patients pooled from 11 natural history studies, there was a statistically and clinically relevant difference in BCVA of 0.33 (+ 16.5 ETDRS) in favour of treated eyes at 48 months after the onset of vision loss ( p A mutation using the technique of allotopic expression, GS010 remains an experimental therapy that has not yet been evaluated by the US Food and Drug Administration (FDA) and the European Medicine Agency (EMA)

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It remains to be determined whether boosting complimentary routes with exogenous substrates, such as citrate, or genetic/pharmacological interventions to increase ME1 or IDH1 levels and/or activity, is sufficient to counteract the excessive oxidative stress and hemolysis seen in G6PD def erythrocytes

This tackles all three simultaneously, which is why women see results in weeks, not years