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After 3 h of OGD treatment in HUVECs, WB results showed that the expression of Ki-67 and Lamin B decreased, while the expression of P53, P21, P16, and -H2AX significantly increased (Figure 3A)

Another example with different in vitro and in vivo performances involves melatonin, a hormone secreted by the pineal gland that plays an important role in sleepwake regulation

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Borah K, Bey M, Theorell A, Wu H, Basu P, Mendum TA, Nh K, Beste DJV, McFadden J