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Angew Chem Int Ed Engl.51(22):5308-32

Zingarelli, B., Day, B

Int J Mol Med (2018) 42:191724

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MANF is predominantly situated on the luminal side of the ER, featuring a C-terminal RTDL sequence that interacts with the KDEL receptor to retain ER and Golgi membrane proteins [143]

For example, the modest response of glioma to bevacizumab is shown, in preclinical studies and clinical case reports, to be due to vessel co-option [100]