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When he looked for small molecules that mimicked the changes created by caloric restriction, he found that both acetyl-L-carnitine and lipoic acid are good mimics

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Mol Genet Metab (2010) 99:5861.10.1016/j.ymgme.2009.08.005 102 FryeRERossignolDA

One of the most frustrating experiences for a patient with chronic fatigue is sitting in a doctor's office, feeling entirely broken, only to be told that their lab results are "perfectly normal." Standard blood panelssuch as Complete Blood Counts (CBC), basic metabolic panels, and routine thyroid testsare designed to detect acute infections, organ failure, or classic autoimmune diseases

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