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doi: 10.1093/hmg/8.5.907
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C2 domains of Munc13-4 are crucial for Ca(2+)-dependent degranulation and cytotoxicity in NK cells
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[1] Cell Line:Jurkat cells Concentration:0.1, 1 and 2 M Incubation Time:24 h Result:Induced dose-dependent apoptosis in Jurkat cells, with the percentage of apoptotic cells increasing from control levels to over 75% at 2 M
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Monotherapy data suggests cagrilintide is effective at 2.4 mg weekly and retatrutide at 8-12 mg weekly, but these doses cannot simply be combined without understanding potential interactions
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