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Crit Care Med 24(3):392397 Fowler AA 3rd, Syed AA, Knowlson S, Sculthorpe R, Farthing D, DeWilde C, Farthing CA, Larus TL, Martin E, Brophy DF, Gupta S, Fisher BJ, Natarajan R (2014) Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis
16 mTORC2, as a growth factor integrating variety of signaling pathway, phosphorylates the 26th serine of SLC7A11 to reduce its activity, thereby inhibiting cystine intake and glutathione metabolism
[DOI] [PMC free article] [PubMed] [Google Scholar] El-Sayed SM, El-Naggar ME, Hussein J, Medhat D, El-Banna M
10.3389/fphys.2017.00910 54 YadavU
In conclusion, our structural and functional analyses provide a large body of novel information for defining the molecular mechanism underlying the activation of c-MET in response to HGF and NK1 and paves the way for the eventual therapeutic intervention of diseases caused by aberrant activation of c-MET
Ensuring adequate protein and calorie intake, even while appetite is suppressed, helps prevent these symptoms
