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Proponents claim it can fix almost any injury, but these assertions are not supported by the kind of rigorous clinical trials required for any approved medical treatment

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In Canada, synthetic injectable peptides are generally regulated as prescription drugs under the Food and Drugs Act, and Health Canada has issued public advisories (April 2026 and earlier) cautioning that unauthorized injectable peptide products are illegal regardless of whether they are labelled 'for research use only.' Research-grade AOD-9604 supplied by Koipeptides is intended for in vitro laboratory study only and is not authorized for any human or veterinary application

The skin acts as a reservoir, allowing the peptide to remain active in the local tissue for many hours, creating a prolonged local effect instead of a short systemic one