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Briefly, mice were euthanized in compliance with the Institutional Animal Care and Use Committee of the Albert Einstein College of medicine and both hippocampi were rapidly removed, placed in ice-cold solution A (0.32 M sucrose, 10 mM HEPES pH 7.4, 1 mM MgCl 2 , 0.5 mM CaCl 2 , protease and phosphatase inhibitors, and 0.1 mM PMSF), and Dounce homogenized

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Immune targets for therapeutic development in depression: towards precision medicine