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Mitochondrial and peroxisomal -oxidation differs in the transport of substrates, substrate specificities, end products, and energy production [19]

TMAO in cardiomyocytes triggers TGF1/Smad3/p65 NFB signaling pathways and lowers energy metabolism and mitochondrial function by disrupting pyruvate and fatty oxidation, as well as the TCA cycle

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Vitamin C and TG Vitamin C supplementation to T2DM patients significantly reduce serum TG with notable heterogeneity, WMD = 11.15 mg/dl (95% CI 21.58, 0.71) p-value = 0.036 and I 2 = 85.7 (Fig