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In the first step, enzymes such as cytochrome P450 monooxygenases catalyze various reactions (oxidation, reduction or hydrolysis) to expose or introduce a functional moiety on hydrophobic substrates

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[DOI] [PubMed] [Google Scholar] 78.Freiherr J., Hallschmid M., Frey W.H., Brnner Y.F., Chapman C.D., Hlscher C., Craft S., De Felice F.G., Benedict C

doi: 10.1093/humupd/dmg027 50 MeucciEMilardiDMordenteAMartoranaGEGiacchiEDe MarinisLet al

According to the Uniport data bank, GPX4 contains 197 residues with a molecular mass of 22 kDa