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2010, pp

In contrast, in the adult human, intravenously administered acetylcarnitine as a bolus (500 mg) led to a rapid increase in plasma concentration followed by a progressive decline reaching the base value in 12 hours
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The dose of melatonin was selected based on that used in previous aging studies in mice 12,16
doi: 10.1016/j.mam.2004.06.002
