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MichaelisMenten type kinetics were determined with a V max of 14.2 0.4 mol min 1 mg 1 and a K m of 2.1 0.2 mM for D-malate (Figure 10B)

ALC also delays the decline of cognitive function in Alzheimer's patients with a 1-year administration at a dosage of 2.0 g/day (CALVANI et al., 1992)

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Cells were washed before measurement by FACS (MACS Quant, Miltenyi Biotec, Bergisch Gladbach, Germany)