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In a corneal neovascularization model, RvE1 inhibited vessel formation by binding to the ChemR23 (also known as ChemR21) [227]

Selenoproteins have antioxidant and enzymatic capacity (47) and, in the thyroid, where they are highly expressed, influence the balance of the cell reduction-oxidation activities (49)

This indicates a hopeful treatment approach by addressing both growth and protective processes at the same time

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Familial Hypocalcemia Hypocalciuria This disease involves a gain-of-function mutation of the calcium-sensing receptor [ CaSR ]