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Description
Each subunit has a typical modular architecture with two large clamshell-like extracellular domains (the N-terminal domain (NTD) involved in assembly and channel modulation and the agonist-binding domain (ABD)), a transmembrane domain (TMD) and a C-terminal domain (CTD) involved in receptor trafficking and signalling
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clinical trial showed significant improvements by week 16
doi: 10.1074/jbc.M113.471235
it actively inhibits microbial growth within the vial following access
