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This cellular priming provides the mechanistic foundation for FOXO4-DRI's selective targeting, enabling researchers to eliminate senescent cells without affecting healthy tissue function
Furthermore, the number of apoptotic cells and the apoptotic index were found to be lower in the Leo20 group than in the control group
The impaired transsulfuration pathway prevented homocysteine transsulfuration to cysteine, resulting in cysteine deficiency and subsequent reduction in GSH pool size
