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Dehydration leads to tearing of the annulus fibrosus (AF) and/or disc herniation, which is clinically characterized by pain and/or neurological signs

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10.1016/j.jhep.2016.12.017 128 StephenneX.NicastroE.EeckhoudtS.HermansC.NyabiO.LombardC.et al (2012)

Kisspeptin is an endogenous peptide hormone encoded by the KISS1 gene and produced in the hypothalamus

However, Skinny Shots are supplements, not prescription drugs, and their effects are typically modest compared with prescription treatments

By enhancing the release of beta-endorphins and modulating pain-related neural circuits, DSIP increases pain tolerance and provides relief from chronic and neuropathic pain