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Currently, the commonly used tVNS in clinical practice includes taVNS, transcutaneous cervical VNS (tcVNS), and closed-loop taVNS (CL-taVNS)

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With prolonged use, the pituitary's baseline GH production decreases a well-documented endocrinological effect

We manually defined the threshold for positive cells on each staining

Unlike earlier compounds such as GHRP-6, Ipamorelin demonstrated greater selectivity, stimulating GH release with minimal off-target hormonal effects