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Drug-Related Discolorations Numerous systemic medications have been implicated in causing oral mucosal pigmentation by either inducing melanin synthesis or by deposition of the drug or its metabolites

Structure and function of the epidermal barrier

Astaxanthin and Obesity: Multi-Organ Metabolic Effects 3.1

Starting at a lower dose and gradually increasing minimizes side effects such as nausea, bloating, and heartburn

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A colesevelam preparation (Cholestagel) is available on the Polish market, and the use of ion exchange resins is currently limited to treatment of severe hypercholesterolaemia during pregnancy