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For example, esculetin (20-60 mg/kg) can inhibit the production of inflammatory factors such as IL-1, IL-6, TNF-, C-C motif chemokine ligand 2 and iNOS in Escherichia coli-induced sepsis mice by inhibiting the NF-B and STAT1/STAT3 signaling pathways (95)
doi: 10.1200/JCO.2014.58.8533

[PubMed] [Google Scholar] 239.Andersson I., Gronberg A., Slinde F., Bosaeus I., Larsson S

A 12-week cycle pairs with a 4-6 week break
Astrocyte schematic reprinted from scidraw.io ( by Chilton J
