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Description
Discover your skin's potential as it inhibits melanin production, revealing a brighter and more youthful complexion.
[PMC free article: PMC4904129] [PubMed: 27379015] 17
Given its role as a significant regulator of cellular metabolism and autophagy, mTORC1 has emerged as an appealing target for pharmacological manipulation of autophagy

For instance, cyclin D1, which is essential for regulating the cell cycle, is downregulated, often due to the dysregulation of the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) pathway

The latter is an imbalance between the generation and elimination of ROS in favor of the former with various consequences for cell physiology (Lushchak, 2014b)

Arterioscler Thromb Vasc Biol 38: 14271439, 2018
