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Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation

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Although the precise mechanism is not known, evidence continues to mount toward one prevailing theory in which the metabolites, phenol and hydroquinone, are central players.45 Second, investigators involved in developing biomarkers of exposure or in understanding the pharmacokinetics of benzene, medicinal products and other chemicals in humans have observed high and widely varying background levels of phenol, hydroquinone and other phenolic species in the blood and urine of control individuals (see below)

11 It has been found that none of the more recently developed antipsychotics except olanzapine have been shown to be superior to FGAs or even to achieve the level of clinical efficacy as attained with clozapine

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Zahir-Jouzdani F, Wolf JD, Atyabi F, Bernkop-Schnrch A