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Description
Classification: DSIP is a small peptide with a sequence of only nine amino acids, making it relatively short and simple compared to other peptides
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Similar to SIRT3, SIRT6 is also activated by fucoidans
The original genetic-validation study used antisense oligonucleotide-mediated knockdown of NNMT in adipose tissue of mice on a high-fat diet, with whole-body and adipose-tissue metabolic endpoints measured against scrambled-oligonucleotide controls [2]
Complete blood cell counts remained within normal limits for all samples taken on days 0, 7, and 14, suggesting that topical applications of TCC and zinc oxide did not result in systemic abnormalities
Most prominent are headache and malaise
