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A: Selank modulates GABAergic transmission, increases BDNF expression, influences serotonin turnover, and regulates cytokine levels including IL-6 and interferon

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Glutathione provides negative feedback on the cycle by inhibiting the enzyme gamma-glutamyl-cysteine synthase

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In addition, pan-Kla has been found to regulate Kmt2a gene transcription in the hippocampal tissue, potentially disrupting synaptic plasticity and affecting cognitive functions in mice, such as spatial exploration and memory, by altering synaptic protein expression [78]

NAD + binding domains are located on top of the N and C-domains