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Lower doses may also be considered on an individual basis for patients that suffer from renal impairment or who are at higher risk of suffering the more severe side effects of the drug (4)

To further investigate whether DSF/Cu facilitates damaged nuclear or mitochondrial DNA leakage into the cytoplasm, we therefore assessed the cytosolic dsDNA with PicoGreen staining

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The primary goal was to assess safety, and it successfully demonstrated no serious adverse effects

A recent investigation has shown that more than 3000 proteins are constitutively S-nitrosated, which are involved in cell signaling and regulation of tissue homeostasis [26,28]

D Western blotting analysis of SLC7A11, GPX4, ACSL4 and PTGS2