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J., Miller, E

We observed a substantial loss of inhibition potency in the corresponding analogs 40, 41, 42 , and 43

DNA Damage, DNA Repair, Aging, and Neurodegeneration

ZBP1 activation led to the recruitment of RIPK3 and caspase-8 to activate the NLRP3 inflammasome, which in turn triggers necroptosis and pyroptosis [116, 117]

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The findings have been supported by linking the overexpression of p62 in the mesenchymal transition to the TLR4p38Nrf2 pathway [102]
