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Notably, satellite cell proliferation plays a pivotal role: in irradiated muscle (with impaired proliferative capacity), FS overexpression produced only ~20% muscle weight gain compared to ~37% in nonirradiated controls, indicating that cell proliferation is essential for the full hypertrophic effect [61]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Nilsson T.K., Yngve A., Bttiger A.K., Hurtig-Wennlf A., Sjstrm M