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Chen J, Chen ZJ (2013) Regulation of NF-B by ubiquitination

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presented a case series on three adolescents who developed redness on the dorsal thenar spaces of both hands while being on doxycycline, coining the term heart sign given the shape of the affected areas when the hands are placed adjacent to one another [129]

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HIF-1 and PFKFB3 mediate a tight relationship between proinflammatory activation and anerobic metabolism in atherosclerotic macrophages