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over-activation of PARP in response to ROS-induced DNA damage initiates an energy-consuming cycle leading to the depletion of intracellular NAD + and ATP culminating into energy failure and cell death [129, 130]

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Smooth muscle cells are inefficient at efferocytosis (199) relying on macrophages to internalize apoptotic smooth muscle cells

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The 3D culture of CM cells in poly-hydroxyethylmethacrylate-coated plates changes the expression of a large variety of transcripts when compared to gene expression profiles of cells cultured in 2D in presence or absence of collagen [156]

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