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Furthermore, in 3D organoid cultures derived from HGSOC patients, replication fork stability was found to correlate with carboplatin sensitivity [31]

28 Half-Life and Steady State If the dose of a drug that is administered is greater than the dose that is eliminated during the dosing interval, it will take about 5 half-lives for a drug to reach steady state levels

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J BioMed Mater Res A (2012) 100:137586

doi: 10.1007/s00438-016-1250-8 80 KangJSongYZhangZWangSLuYLiuX

Cocaine and the blood-brain-barrier
