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The assessment of mechanical allodynia is performed by using a set of von Frey monofilaments which provide a calibrated force to a portion of the subjects body (Figure 1A)

Allopurinol and febuxostat are medications used to reduce the amount of uric acid produced in the body

Marburg virus (MARV) hijacks KEAP1-NRF2 signaling by targeting KEAP1, thus activating NRF2, in order to decrease host immune responses [134]

Mitochondria are pivotal in both energy generation and cellular pathways, exhibiting a wide range of functional diversities that are paralleled by their structural and morphological variability throughout the cell cycle [13]

Since MRS detects only free CHO and water-soluble membrane breakdown products (eg, phosphocholine and glycerophosphocholine), elevated CHO is often interpreted as evidence of abnormal phospholipid metabolism and increased cell membrane turnover, consistent with glial proliferation and neuroinflammatory processes