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However, insulin follows the path of least resistance when directing glucose, so if muscle tissue receives glucose more easily, it will be preferentially stored there and not in fat

Chalmers JD, Smith MP, McHugh BJ, Doherty C, Govan JR, Hill AT

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Further, more strategies to reduce toxicity based on pathophysiological mechanisms of neurotoxicity are necessary

doi: 10.1038/s41580-020-0230-3 3 ShekhovaE

Curcumin-PLGA nanoparticles were administered intravenously every two days (6 doses in total), followed by LIFU-mediated BBB opening at an acoustic pressure of 0.45 MPa