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Endoplasmic reticulum stress in hepatic stellate cells promotes liver fibrosis via PERK-mediated degradation of HNRNPA1 and up-regulation of SMAD2

Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling

Misrani A, Tabassum S, Yang L

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In another study, RNA-seq data of intestinal biopsies from ulcerative colitis patients were analysed with QIIME, revealing an inverse correlation with the abundance of Akkermansia and Bifidobacteria , microbes known for their anti-inflammatory properties [100]

This rapid neutralization prevents ROS from tearing electrons away from healthy cellular structures, effectively putting out the biochemical fires driving chronic inflammation