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Further, AC blocks the phosphorylation of key MAPKs including ERK1/2, JNK, and p38 as the upstream regulators of transcription factors involved in inflammation (Ling et al
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A landmark 2012 study using the Broad Institute's Connectivity Map identified that GHK-Cu could modulate the expression of 4,048 genes roughly 6% of the human genome

Acknowledgements The authors would like to thank Christopher Ware and Gain Robinson for histology recommendations and consulting on the DT-MRI analysis, respectively.
