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Polylactic acid NPs encapsulating cisplatin in the inner core with a cationic coating of chitosan that consists of ionically linked P62siRNA (siP62) and/or 5 expressing plasmid DNA (p5) as the outer layer were synthesized and their treatment on cisplatin resistance OC cells exhibited increased sensitivity toward cisplatin [55]

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Frontier molecular orbital (FMO) studies FMO studies could predict the chemical reactivity of compounds and identify their most likely reactive sites

For the most part, that guidance holds up

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However, it is noteworthy that patients with HT-induced hypothyroidism may continue to experience persistent symptoms despite achieving normal serum levels of TSH and thyroxine (T4) [14]