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10.3390/cells13010070 4 Avila-CarrascoL.MajanoP.Snchez-TomroJ

Overactivated M1 macrophages exacerbate inflammation through secreting pro-inflammatory cytokines, driving joint damage, whereas immunosuppressive M2 macrophages are diminished, disrupting immune equilibrium (130)

As a result, your skin looks healthier, feels softer, and is better equipped to fight off dryness

Moreover, stimulation of Nrf2 can negatively modulate ferroptosis through iron, glutathione, lipid metabolism as well as mitochondrial function [32]

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