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60,61 A third redox-sensitive pathway groupincluding Wnt/-catenin, PI3K/AKT/mTOR, aryl hydrocarbon receptor (AhR), TGF-, calcium signaling, Janus kinase (JAK)/signal transducers and activators of transcription (STAT), hypoxia-inducible factor 1 (HIF1), NF-B, Nrf2, c-Jun N-terminal kinase (JNK), p38, and Ataxia-telangiectasia mutated (ATM)features components that shuttle between the cytoplasm and nucleus, allowing complex regulation of gene expression and cellular fate

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Hampel H., Nistico R., Seyfried N.T., Levey A.I., Modeste E., Lemercier P., Baldacci F., Toschi N., Garaci F., Perry G., et al

The dorsal skin tissue was polymerized at 36 to 60C, ultrathin sections were made, cells from hair follicles were selected, and they were collected on a copper mesh

Excess iron is also detrimental to the body, and is associated with an increased risk of cancer, neurodegenerative diseases, and diabetes [4]