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Toxic and inflammatory burden can increase glutathione and detoxification demand, impair mitochondrial energy production and alter homocysteine metabolism

Nat Rev Cancer 15(12):701711 Pinthus JH et al (2007) Androgen induces adaptation to oxidative stress in prostate cancer: implications for treatment with radiation therapy

Glutamine helps nourish intestinal tissues, arabinogalactan provides prebiotic support for beneficial gut bacteria, and DGL with aloe vera help soothe and support the GI tract for a more balanced digestive environment.*

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Recently, studies revealed conditioned media and EVs isolated from human mesenchymal stem cells (MSCs) are potent in reducing senescent cell burden and may serve as novel senolytic strategy (Figure 2)