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Coordination of mitochondrial biogenesis by thyroid hormone

Neuroprotective Effects Preliminary preclinical research suggests silymarin may have neuroprotective properties, with in vitro and animal studies indicating potential to protect brain cells from oxidative stress and inflammation [3][44]

The timing of immune checkpoint inhibitors and other immunotherapeutic agents can be optimized to align with the circadian regulation of immune responses, potentially enhancing anti-tumor immunity and improving patient outcomes [110]

While most CIPN occurs in a dose dependent fashion, other drug-specific features may be present such as the acute neurotoxicity of paclitaxel and oxaliplatin, or the worsening of neuropathy after discontinuation of cisplatin (coasting)

Ferritin Reduction and Oxidative Stress Management Glutathione also helps reduce ferritin levels, which can be elevated in NAFLD and contribute to oxidative stress and liver damage

Am J Surg Pathol 42(6):705-714, 2018