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When barrier integrity is impaired, microbial products may activate Toll-like receptor 4 (TLR4)-myeloid differentiation primary response gene 88 (MyD88)-nuclear factor-kappa B (NF-B) signaling and amplify proinflammatory cascades, further aggravating barrier dysfunction [67]

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doi: 10.1016/j.envexpbot.2012.02.013 60 PottersG.HoremansN.JansenM

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