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Thiostrepton: a novel therapeutic drug candidate for Mycobacterium abscessus infection

Secreted elastase activity (U/mL) from PsA sputum isolates taken pre- and post-therapy from ( A ) patient 1 (N pre =1, N post =3, p=NA), ( B ) patient 2 (N pre =4, N post =5, p=0.2857), ( C ) patient 3 (N pre =1, N post =1, p=NA), ( D ) patient 4 (N pre =1, N post =6, p=NA), ( E ) patient 5 (N pre =2, N post =4, p=0.3333), ( F ) patient 6 (N pre =3, N post =3, p=0.2032), ( G ) patient 7 (N pre =2, N post =5, p=0.2381), ( H ) patient 8 (N pre =3, N post =1, p=NA), and ( I ) patient 9 (N pre =1, N post =3, p=NA)

2010;21(7):vii15464

Hot water extraction is then used to break down the yeast cells, releasing their nutrients

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