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53, 12831304.10.1093/jexbot/53.370.939 48 NoctorG.StrohmM.JouaninL.KunertK

Animal toxicology studies extended longer

(2000) Evaluation of low-dose endotoxin administration during pregnancy as a model of preeclampsia

Also in this setting, the potency of FOXO4-DRI was more pronounced when applied in consecutive rounds Not only did FOXO4-DRI selectively target the senescent cells, but it was also effective agains the induced chemo-toxicity observed in the form of liver toxicity and body weight loss

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This is in line with the essential biochemical role all three B vitamins have (see introduction) in energy metabolism [10,12]