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IGF-1 levels have been shown to be decreased in children with Meningococcal sepsis and more so in those for whom the infection was fatal [83]

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Drug intake, sudden and uncommon age of onset, pruritus, a monomorphic pattern and an involvement of extra-seborrheic areas are features that distinguish acneiform eruptions from acne vulgaris

Patients should ensure they are registered with a GP who is aware of their surgical history and should attend all recommended follow-up appointments, as early detection of deficiency allows for timely intervention before irreversible complications develop

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