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PLoS ONE 2012, 7, e37779

Additionally, changes in the microenvironment, such as redox state, altered pH, and the presence of reactive oxygen species (ROS) at the pathophysiological sites, can act as sensitive stimuli to trigger drug release in those areas

PRISMA reporting guidelines were used to select 56 articles with a total of 126 patients with hydroquinone-associated ochronosis

Sympathoadrenal neural crest cells: the known, unknown and forgotten

Cigarette smoking and coronary heart disease: risks and management

Research from Oxford University demonstrates that mepolizumab not only reduces eosinophil counts but reverses the primed hyperactive state these cells develop in severe asthma. This treatment is specifically designed for patients with severe eosinophilic asthma , defined as having blood eosinophil levels of 150 cells per microliter or higher despite using high-dose inhaled corticosteroids plus additional controllers