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GATOR1 inhibits mTORC1 signaling, while GATOR2 positively regulates mTORC1 and inhibits GATOR1 by forming a complex at the lysosomal membrane ( 2.3.2 TRIM16 TRIM16 has been identified as a regulator of oxidative-stress-responsive proteins (Ren X

Activation of the indole-3-acetic acid-amido synthetase GH3-8 suppresses expansin expression and promotes salicylate- and jasmonate-independent basal immunity in rice

cGAS can be activated by any dsDNA in a sequence independent manner to activate cGAS-STING signaling pathway, which has been reported to be a critical pathway for anti-tumor, antiviral and anti-bacterial defense (53, 103)

ABC sub-family A transporters, a group of well-known cholesterol transporters, are also related to CRC resistance

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PXN inhibits phosphodiesterase 9 (PDE9), which terminates nitric oxide (NO) neurotransmission by metabolizing cyclic guanosine monophosphate (cGMP) back to GMP