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Mechanistic studies reveal that JMJD3 facilitates TGF-/Smad signaling and epithelialmesenchymal transition (EMT) by regulating syntenin, a scaffolding protein that enhances TGF- signaling

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6.3 Alcohol Alcoholic liver disease patients have low hepatic and plasma GSH levels due to multiple mechanisms such as oxidative stress, nutritional deficiency and abnormalities in the methionine metabolic pathway that impairs cysteine availability [164166]
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