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J Clin Invest 73(3):785793 Caudill MA, Dellschaft N, Solis C, Hinkis S, Ivanov AA, Nash-Barboza S, Randall KE, Jackson B, Solomita GN, Vermeylen F (2009) Choline intake, plasma riboflavin, and the phosphatidylethanolamine N -methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype

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201 Secondly, copper can directly or indirectly influence the activity of various proteins involved in apoptotic pathways